PyBDC/Verification.py

#!/usr/bin/env python3
# -*- coding: utf-8 -*-

"""
Verification code using Sarno any spectrum for a breast with a diamter 16 cm, radius of 2xradius, and glandularity of 50%. Using the defined keV, I, and coefficients the normalized glandular dose can be computed. The correct value for these parameters
is 0.03614995451146596. The mean glandular dose was computed using the parameters of 300 projections, 0.5 mAs, and an input air kerma of 5 mR.

"""

import sys
import numpy as np
from dose_equations import (
    Sarno_mono_dgn,
    Sarno_poly_dgn,
    sarno_dgnct,
    Hernandez_hetero_mono_dgn,
    exposure_per_fluence,
    Sechopoulos_poly_dgn,
)


def exposure_per_fluence(E):
    exposure = np.zeros(len(E))
    for i in range(len(exposure)):
        keV = E[i]
        temp = (
            (
                (
                    -5.023290717769674e-6
                    + 1.810595449064631e-7
                    + np.sqrt(keV)
                    + np.log(keV)
                    + 0.008838658459816926 / keV**2
                )
                ** (10**-3)
            )
            / 1000
            * 0.1145
        )
        exposure[i] = temp
    return exposure


def dgn_calculate(a, b, c, d, e, f, g, h, keVs):
    dgn = np.zeros(len(keVs))
    for i in range(len(keVs)):
        E = keVs[i]
        temp = (
            a * 10 ** (-14) * E**8
            + b * 10 ** (-12) * E**7
            + c * 10 ** (-10) * E**6
            + d * 10 ** (-8) * E**5
            + e * 10 ** (-6) * E**4
            + f * 10 ** (-4) * E**3
            + g * 10 ** (-3) * E**2
            + h * 10 ** (-2) * E
        )
        dgn[i] = temp
    return dgn


def pDgN_calculate_denominator(I, exposure):
    total = I * exposure
    pDgN_denom = np.sum(total)

    return pDgN_denom


def pDgN_calculate_numerator(I, dgn, exposure):
    total = I * exposure * dgn
    pDgN_num = sum(total)
    return pDgN_num


def calculate_pDgNct(*values):
    keV = values[2]
    I = values[3]
    psiE = np.array(list(map(exposure_per_fluence, keV)))

    if values[0] == "Sarno Koning":
        variables = values[1]
        DgNctE = np.array(
            list(
                map(
                    sarno_dgnct,
                    variables[:, 0],
                    variables[:, 1],
                    variables[:, 2],
                    variables[:, 3],
                    variables[:, 4],
                    variables[:, 5],
                    variables[:, 6],
                    variables[:, 7],
                    keV,
                )
            )
        )
        pDgN = np.sum(I * psiE * DgNctE) / np.sum(I * psiE)
    elif values[0] == "Hernandez":
        DgN_list = np.array(values[1])
        pDgN = np.sum(I * psiE * DgN_list) / (np.sum(I * psiE))

    return pDgN


# calculate mgd input air kerma for 1 projection
def calculate_mgd(
    air_KERMA, dgn, number_of_projections, mAs, air_KERMA_input_units, output_units
):
    # Convert air kerma input to mGy if it is not already in mGy
    if air_KERMA_input_units != "mGy":
        if air_KERMA_input_units == "mrad":
            air_KERMA = air_KERMA * 0.01  # convert from mrad air kerma to mGy
        elif air_KERMA_input_units == "R":
            air_KERMA = air_KERMA * 8.77  # convert from R to mGy
        elif air_KERMA_input_units == "mR":
            air_KERMA = air_KERMA * 0.00877  # convert from mR to mGy

    # Calculate MGD in mGy/mGy
    mgd = air_KERMA * dgn * float(number_of_projections) * mAs

    # Convert MGD to mrad if output units are mrad
    if output_units == "mrad":
        mgd = mgd * 100  # converts mgd to mrad

    return mgd


a = -0.41324119391158
b = 4.88540710576677
c = -13.0460380815292
d = 15.3913804609064
e = -9.19621868949206
f = 2.66123817129083
g = -2.67974610124986
h = 0.883219836298924

air_KERMA = 5.0  # mR
number_of_projections = 300
mAs = 0.5

keV = np.array([10, 10.5, 11, 11.5, 12, 12.5, 13, 13.5, 14])
I = np.array(
    [
        6.20275e2,
        2.26229e2,
        5.25667e2,
        2.39324e3,
        1.45979e3,
        2.17293e3,
        3.36611e3,
        4.89394e3,
        6.61405e3,
    ]
)

exposure = exposure_per_fluence(keV)
dgn = dgn_calculate(a, b, c, d, e, f, g, h, keV)

pDgN_num = pDgN_calculate_numerator(I, dgn, exposure)
pDgN_denom = pDgN_calculate_denominator(I, exposure)
pDgN = pDgN_num / pDgN_denom

print("pDgN =", pDgN)

mgd = calculate_mgd(air_KERMA, pDgN, number_of_projections, mAs, "mR", "mGy")

print("mgd =", mgd)