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  ### Dataset Description
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- This dataset contains **1,000 synthetic 3D chest CT scans** generated using the model introduced in
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- [*From Alignment to Synthesis: Contrastive Volumetric Grounding for Text-to-CT Generation*](https://arxiv.org/abs/2506.00633) (Molino et al., BMVC 2026).
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- The model was trained on the **CT-RATE dataset**, the largest publicly available collection of paired CT volumes and radiology reports.
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  It leverages a **3D latent diffusion framework** combined with **contrastive vision-language pretraining (3D-CLIP)** to synthesize anatomically coherent and semantically faithful CT scans directly from clinical text prompts.
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  These 1,000 scans were generated for the **VLM3D Challenge - Task 4**, serving as a benchmark resource for multimodal evaluation and synthetic data research in medical imaging.
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- > **Note.** These scans were generated with the earlier version of the model ([arXiv v2](https://arxiv.org/abs/2506.00633v2)), the one submitted to the VLM3D Challenge.
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-
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- - **Curated by:** ArCo Lab – Università Campus Bio-Medico di Roma & Umeå University
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- - **Language(s):** Conditioning reports are in English
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  - **License:** Apache 2.0
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  ### Dataset Sources
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- - **Repository:** [GitHub Repository](https://github.com/cosbidev/Text2CT)
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- - **Paper:** [arXiv:2506.00633](https://arxiv.org/abs/2506.00633)
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- - **Challenge:** [VLM3D Challenge](https://vlm3dchallenge.com)
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  ## Uses
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  ### Direct Use
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-
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  - Benchmarking text-to-CT generative models.
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  - Data augmentation for classification, detection, or segmentation tasks.
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  - Research in multimodal vision-language learning for 3D medical imaging.
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  - Educational purposes and simulation in medical training.
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  ### Out-of-Scope Use
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-
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- - Direct diagnostic or clinical use.
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- - Deployment in healthcare without proper validation and regulatory approval.
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  - Any attempt to re-identify patients (note: scans are fully synthetic).
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  ## Dataset Structure
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- - **Format:** Volumetric CT scans stored in NIfTI (`.nii.gz`) format.
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- - **Resolution:** Resampled to 0.75 × 0.75 × 3.0 mm voxel spacing, cropped/padded to 512 × 512 × 128.
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- - **Intensity:** Normalized in Hounsfield Units (clipped to [−1000, +1000]).
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- - **Content:** Synthetic chest CT scans across 18 pathological conditions (e.g., nodules, opacities, effusion, emphysema).
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  ## Dataset Creation
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  ### Curation Rationale
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-
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  Created to provide a reproducible benchmark for **text-to-CT generation** and to supply **synthetic volumetric data** for research in data augmentation, privacy preservation, and multimodal foundation models.
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  ### Source Data
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-
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  - Trained on **CT-RATE** (Hamamci et al., 2024), a large-scale dataset of chest CTs paired with radiology reports.
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  ### Annotations
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-
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  No manual annotations included; diagnostic semantics are embedded via the conditioning text prompts used during generation.
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  ### Personal and Sensitive Information
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-
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- - The dataset contains **no real patient data**.
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  - All scans are **synthetic** and generated by a model trained on anonymized public datasets.
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  ## Bias, Risks, and Limitations
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- - Synthetic data may not fully capture rare pathologies or distributional nuances of real-world scans.
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- - While useful for augmentation and benchmarking, these scans are **not clinically validated**.
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  - There is a potential risk if synthetic data are used without acknowledging their limitations in medical research.
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  ### Recommendations
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-
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- Users should:
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-
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- - Combine synthetic with real-world data for downstream tasks.
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- - Avoid over-relying on synthetic volumes for clinical translation.
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  - Report the provenance of synthetic data when used in publications.
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  ## Citation
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  If you use this dataset, please cite the following work:
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  **BibTeX:**
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-
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- ```bibtex@misc{molino2026alignment,
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- title={From Alignment to Synthesis Contrastive Volumetric Grounding for Text-to-CT Generation},
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- author={Daniele Molino and Camillo Maria Caruso and Filippo Ruffini and Paolo Soda and Valerio Guarrasi},
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- year={2026},
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- eprint={2506.00633},
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- archivePrefix={arXiv},
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- primaryClass={cs.CV},
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- url={https://arxiv.org/abs/2506.00633},
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  }
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  ```
 
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  ### Dataset Description
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+ This dataset contains **1,000 synthetic 3D chest CT scans** generated using the model introduced in
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+ [*Text-to-CT Generation via 3D Latent Diffusion Model with Contrastive Vision-Language Pretraining*](https://arxiv.org/abs/2506.00633) (Molino et al., 2025).
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+ The model was trained on the **CT-RATE dataset**, the largest publicly available collection of paired CT volumes and radiology reports.
24
  It leverages a **3D latent diffusion framework** combined with **contrastive vision-language pretraining (3D-CLIP)** to synthesize anatomically coherent and semantically faithful CT scans directly from clinical text prompts.
25
 
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  These 1,000 scans were generated for the **VLM3D Challenge - Task 4**, serving as a benchmark resource for multimodal evaluation and synthetic data research in medical imaging.
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+ - **Curated by:** ArCo Lab Università Campus Bio-Medico di Roma & Umeå University
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+ - **Language(s):** Conditioning report are in English
 
 
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  - **License:** Apache 2.0
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  ### Dataset Sources
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+ - **Repository:** [GitHub Repository](https://github.com/cosbidev/Text2CT)
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+ - **Paper:** [arXiv:2506.00633](https://arxiv.org/abs/2506.00633)
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+ - **Challenge:** [VLM3D Challenge](https://vlm3dchallenge.com)
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  ## Uses
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  ### Direct Use
 
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  - Benchmarking text-to-CT generative models.
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  - Data augmentation for classification, detection, or segmentation tasks.
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  - Research in multimodal vision-language learning for 3D medical imaging.
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  - Educational purposes and simulation in medical training.
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  ### Out-of-Scope Use
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+ - Direct diagnostic or clinical use.
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+ - Deployment in healthcare without proper validation and regulatory approval.
 
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  - Any attempt to re-identify patients (note: scans are fully synthetic).
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  ## Dataset Structure
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+ - **Format:** Volumetric CT scans stored in NIfTI (`.nii.gz`) format.
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+ - **Resolution:** Resampled to 0.75 × 0.75 × 3.0 mm voxel spacing, cropped/padded to 512 × 512 × 128.
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+ - **Intensity:** Normalized in Hounsfield Units (clipped to [−1000, +1000]).
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+ - **Content:** Synthetic chest CT scans across 18 pathological conditions (e.g., nodules, opacities, effusion, emphysema).
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  ## Dataset Creation
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  ### Curation Rationale
 
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  Created to provide a reproducible benchmark for **text-to-CT generation** and to supply **synthetic volumetric data** for research in data augmentation, privacy preservation, and multimodal foundation models.
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  ### Source Data
 
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  - Trained on **CT-RATE** (Hamamci et al., 2024), a large-scale dataset of chest CTs paired with radiology reports.
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  ### Annotations
 
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  No manual annotations included; diagnostic semantics are embedded via the conditioning text prompts used during generation.
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  ### Personal and Sensitive Information
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+ - The dataset contains **no real patient data**.
 
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  - All scans are **synthetic** and generated by a model trained on anonymized public datasets.
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  ## Bias, Risks, and Limitations
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+ - Synthetic data may not fully capture rare pathologies or distributional nuances of real-world scans.
76
+ - While useful for augmentation and benchmarking, these scans are **not clinically validated**.
77
  - There is a potential risk if synthetic data are used without acknowledging their limitations in medical research.
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  ### Recommendations
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+ Users should:
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+ - Combine synthetic with real-world data for downstream tasks.
82
+ - Avoid over-relying on synthetic volumes for clinical translation.
 
 
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  - Report the provenance of synthetic data when used in publications.
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  ## Citation
 
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  If you use this dataset, please cite the following work:
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  **BibTeX:**
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+ ```bibtex
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+ @article{molino2025textct,
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+ title={Text-to-CT Generation via 3D Latent Diffusion Model with Contrastive Vision-Language Pretraining},
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+ author={Molino, Daniele and Caruso, Camillo Maria and Ruffini, Filippo and Soda, Paolo and Guarrasi, Valerio},
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+ journal={arXiv preprint arXiv:2506.00633},
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+ year={2025}
 
 
 
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  }
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  ```